Laboratório de Genética do Comportamento

 

   LISTA DE PUBLICAÇÕES

SELECTED LIST OF PUBLICATIONS

TCC
RAMOS, A. A. (1986). Estudo Comparativo do Comportamento do Gado Crioulo Lageano e do Gado Nelore. 

Este trabalho, publicado em 1986 por Ramos e colaboradores, marca o início dos estudos em Etologia Aplicada na UFSC, bem como está nos primórdios da história do Laboratório de Genética do Comportamento, já que foi naquela ocasião que seu fundador, Prof. André Ramos, se iniciou nas ciências e no estudo do comportamento animal, ainda como aluno de graduação da UFSC.

This piece of work, published in 1986 by Ramos and colleagues, sets the begining of the studies on Applied Ethology at UFSC. It is also somehow part of the history of the Behavioral Genetics Laboratory, since it was at that time that its founder, Prof André Ramos, was initiated as a junior scientist and in the study of animal behavior, still as a undergraduate student at UFSC.

EDITED BOOK
Ramos, A., Pinheiro Machado Filho, L.C. and Hötzel, M.J. (Editors) (2000). Proceedings of the 34th International Congress of the ISAE (International Society for Applied Ethology). Laboratório de Etologia Aplicada / UFSC,Florianópolis, 240 p.

BOOK CHAPTERS
Mormède, P. and Ramos, A. (1999). Genetics and emotional behaviors – experimental studies. In: Neurobehavioral Genetics: Methods and Applications (Jones, B.C. and Mormède, P., eds.). CRC Press, Boca Raton, pp 301-315.

 

Ramos, A. and Mormède, P. (2006). Genetics analysis of emotional behaviors using animal models. In: Neurobehavioral Genetics: Methods and Applications, 2^nd edition (Jones, B.C. and Mormède, P., eds.). CRC Press, Boca Raton, pp 291-306.

 

Moisan, M-P. and Ramos, A. (2010). Rat Genomics applied to psychiatric research. In: Rat Genomics: Methods and Protocols, Methods in Molecular Biology, vol. 597 (Anegon, I., ed). Humana Press pp 357-388.

 

Prediger, Rui Daniel; França, Angela Patricia; IZÍDIO, GEISON SOUZA; Takahashi, Reinaldo Naoto (2018). The Use of Object Recognition Task in Animal Models of Attention-Deficit Hyperactivity Disorder. In: Abdel Ennaceur; Maria de Souza Silva. (Org.). Handbook of Behavioral Neuroscience. 1ed.Nova Iorque: Elsevier, v. 27, p. 341-357.
Granzotto, Natalli; Araújo, Julia Fernandez Puñal; Carvalho, Daniela Machado Alexandre; IZÍDIO, GEISON SOUZA (2019). A IMPORTÂNCIA HISTÓRICA DOS RATOS NO AVANÇO DA COMPREENSÃO DA BIOLOGIA HUMANA. In: Valeska Regina Reque Ruiz. (Org.). Comportamento animal. 1ed.Ponta Grossa: Antonella Carvalho de Oliveira, v. 1, p. 1-17.

REVIEWS
Ramos, A. and Mormède, P. (1998). Stress and emotionality: a multidimensional and genetic approach. Neurosci. Biobehav. Rev. 22: 33-57.

Mormède, P., Courvoisier, H., Ramos, A., Marissal-Arvy, N., Ousova, O., Désautés, C., Duclos, M., Chaouloff, F. and Moisan, M.-P. (2002). Molecular genetic approaches to investigate individual variations in behavioral and neuroendocrine stress responses. Psychoneuroendocrinology 27: 563-583.

Vendruscolo, L. F.; Izídio, G. S.; Takahashi, R. N. (2009). Drug Reinforcement in a Rat Model of Attention Deficit/Hyperactivity Disorder – The Spontaneously Hypertensive Rat (SHR). Current Drug Abuse Reviews, 2:177-183

Vitor de Castro Gomes, Waseem Hassana, Silvia Maisonnettea, Luke R. Johnsonb, André Ramos, J. Landeira-Fernandeza. (2013). Behavioral evaluation of eight rat lines selected for high and low anxiety-related responses. Behav. Brain Res. 257: 39-48.

ARTICLES
Ramos, A., Berton, O., Mormède, P. and Chaouloff, F. (1997). A multiple-test study of anxiety-related behaviours in six inbred rat strains. Behav Brain Res 85: 57-69.

Berton, O., Ramos, A., Chaouloff, F. and Mormède, P. (1997). Behavioral reactivity to social and nonsocial stimulations: a multivariate analysis on six inbred rat strains. Behav Genet 27: 155-166.

Kulikov, A., Aguerre, S., Berton, O., Ramos, A., Mormède, P. and Chaouloff, F. (1997). Central serotonergic systems in the spontaneously hypertensive and Lewis rat strains that differ in the elevated plus-maze test of anxiety. J Pharmacol Exp Ther 281: 775-784.

Ramos, A., Mellerin, Y., Mormède, P. and Chaouloff, F. (1998). A genetic and multifactorial analysis of anxiety-related behaviours in Lewis and SHR intercrosses. Behav Brain Res. 96: 195-205.

Ramos, A., Moisan, M-P., Walentinsson, A., Sjoling, A., Klinga-Levan, K., Atkinson, O.S., Jacob, H.J., Thomas, M., Grob , U. and Knoblauch, M. (1998). Discrepancies in chromosomal assignment of commercially available rat microsatellite markers. Rat Genome 4: 103-110.

Ramos, A., Moisan, M-P., Chaouloff, F. and Mormède, P. (1998). Estresse: em busca de genes responsáveis pela variabilidade interindividual. Rev Etol número especial: 41-52.

Cook, M.N., Ramos, A., Courvoisier, H. and Moisan, M-P. (1998). Linkage mapping of a 3, a 5 and b 4 neuronal nicotinic acetylcholine receptors to rat chromosome 8. Mamm Genome 9: 177-178.

Ramos, A., Moisan, M-P., Chaouloff, F., Mormède, C. and Mormède, P. (1999). Identification of female-specific QTLs affecting an emotionality-related behavior in rats. Mol Psychiatry 4: 453-462.

Ramos, A., Kangerski, A.L., Basso, P.F., Santos, J.E.S., Assreuy, J., Vendruscolo, L.F. and Takahashi, R.N. (2002). Evaluation of Lewis and SHR rat strains as a genetic model for the study of anxiety and pain. Behav Brain Res 129: 113-123.

Ramos, A., Correia, E.C., Izídio, G.S. and Brüske, G.R. (2003). Genetic selection of two new rat lines displaying different levels of anxiety-related behaviors.  Behav Genet 33 (6): 657-668.

Vendruscolo, L.F., Takahashi, R.N., Brüske, G.R. and Ramos, A. (2003). Evaluation of the anxiolytic-like effect of NKP608, a NK1-receptor antagonist, in two rat strains that differ in anxiety-related behaviors. Psychopharmacology 170: 287-293.

Da Silva, G.E., Ramos, A., Takahashi, R.N. (2004). Comparison of voluntary ethanol intake by two pairs of rat lines used as genetic models of anxiety. Braz J Med Biol Res 37 (10): 1511-1517.

Izídio, G.S., Lopes, D.M., Spricigo Jr, L., Ramos, A. (2005). Common variations in the pre-test environment influence genotypic comparisons in models of anxiety. Genes Brain Behav 4: 412-419.

Izídio, G.S., Spricigo Jr, L., Ramos, A. (2005). Genetic differences in the elevated plus-maze persist after first exposure of inbred rats to the test apparatus. Behav Proc 68 (2): 129-134.

Hinojosa, F.R.,  Spricigo Jr, L., Izídio, G.S., Brüske, G.R., Lopes, D.M. and Ramos, A (2006). Evaluation of two genetic animal models in behavioral tests of anxiety and depression. Behav Brain Res 168: 127-136.

Vendruscolo, L. F., Rigaldie, E. T., Raba, F., Ramos, A., Takahashi, R. N., Mormède, P. (2006). Evidence for a female-specific effect of a chromosome 4 locus on anxiety-related behaviors and ethanol drinking in rats. Genes Brain Behav 5: 441-450.

Vendruscolo, L. F., Rigaldie, E. T., Raba, F., Ramos, A., Takahashi, R. N., Mormède, P. (2006). A QTL on rat chromosome 7 modulates prepulse inhibition, a neuro-behavioral trait of ADHD, in a Lewis x SHR intercross. Behav Brain Func v. 2, n. 21.

Vendruscolo, L. F., Vendruscolo, J. C. M., Rigaldie, E. T., Raba, F., Ramos, A., Takahashi, R. N., Mormède, P. (2006). Genetic influences on behavioral and neuroendocrine responses to predator odor stress in rats. Neurosci Lett 409: 89-94.

Brüske, G.R., Vendruscolo, L.F. and Ramos, A. (2007). Two inbred rat strains contrasting for anxiety-related behaviors show similar levels of defensive responses to cat odor. Behav Brain Func v. 3, n. 17.

Izídio, G.S.,  Ramos, A. (2007). Positive association between ethanol consumption and anxiety-related behaviors in two selected rat lines. Alcohol 41: 517-524.

Vendruscolo, L.F. , Izídio, G.S.,  Takahashi, R. N., Ramos, A. (2008). Chronic methylphenidate treatment during adolescence increases anxiety-related behaviors and ethanol drinking in adult Spontaneously Hypertensive Rats. Behav Pharmacol 19: 21-27.

Ramos, A., Pereira, E., Martins, G.C., Wehrmeister, T.D., Izídio, G.S. (2008). Integrating the open field, elevated plus maze and light/dark box to assess different types of emotional behaviors in one single trial. Behav Brain Res 193: 277-288.

Hameister, T.M.,  Izídio, G.S., Valiati, V.H., Ramos, A. (2008). Association of a locus on rat chromosome 4 with anxiety-related behaviors in two selectively bred rat lines. Gen Mol  Biol 31, 4, 843-849.

Ramos, A. (2008). Animal models of anxiety: do I need multiple tests. Trends Pharmacol Sci 29: 493-498.

Chiavegatto, S., Izidio, G.S., Mendes-Lana, A., Aneas, I., Freitas, T.A., Torrão, A.S., Conceição, I.M., Britto, L.R.G., Ramos, A. (2009). Expression of α-synuclein is increased in the hippocampus of rats with high levels of innate anxiety. Mol Psychiatry 14: 894-905.

Vendruscolo, L. F., Vendruscolo, J. C. M., Terenina, E., Ramos, A., Takahashi, R. N., Mormède, P. (2009). Marker-assisted dissection of genetic influences on motor and neuroendocrine sensitization to cocaine in rats. Genes Brain Behav 8:267-274.

Ribeiro AM, Barbosa FF, Godinho MR, Fernandes VS, Munguba H, Melo TG, Barbosa MT, Eufrasio RA, Cabral A, Izídio GS, Silva RH. (2009). Sex differences in aversive memory in rats: possible role of extinction and reactive emotional factors. Brain Cogn. 2010 Nov;74(2):145-51.

Fraser, L.M., Brown, R.E., Hussin, A., Fontana, M., Whittaker, A., O’Leary, T.P., Lederle, L., Holmes, A., Ramos, A. (2010). Measuring anxiety- and locomotion-related behaviours in mice: a new way of using old tests. Psychopharmacology 211:99-112.

Wehrmeister, T.D., Izídio, G.S., Pereira, E., Izídio, G., Ramos, A. (2010). Absence of repeated-trial tolerance to the anxiolytic-like effects of chlordiazepoxide in the rat triple test. Pharmacol Biochem Behav 97:301-309.

Munguba H, Cabral A, Leão AH, Barbosa FF, Izídio GS, Ribeiro AM, Silva RH. (2011). Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats. Neurobiol Learn Mem 95(4):527-33.

Izídio, G.S., Oliveira, L.C., Oliveira, L.F.G., Pereira, E., Wehrmeister, T.D., Ramos, A. (2011). The influence of sex and estrous cycle on QTL for emotionality and ethanol consumption. Mamm Genome 22:329-340.

Hussin, A.T., Fraser, L.M., Ramos, A., Brown, R.E. (2012). The effect of chlordiazepoxide on measures of activity and anxiety in Swiss-Webster mice in the triple test. Neuropharmacology 63: 883-889.

Fernandes VS, Santos JR, Leão AH, Medeiros AM, Melo TG, Izídio GS, Cabral A, Ribeiro RA, Abílio VC, Ribeiro AM, Silva RH. (2012). Repeated treatment with a low dose of reserpine as a progressive model of Parkinson’s disease. Behav Brain Res 16;231(1):154-63.

Melo TG, Izídio GS, Ferreira LS, Sousa DS, Macedo PT, Cabral A, Ribeiro AM, Silva RH. (2012). Antidepressants differentially modify the extinction of an aversive memory task in female rats. Prog Neuropsychopharmacol Biol Psychiatry 27;37(1):33-40.

Silva FR, Cabral A, Lima AP, Dierschnabel AL, Nascimento EB, Macedo PT, Izídio GS, Ribeiro AM, Silva RH. (2013) The Anabolic Androgenic Steroid Testosterone Propionate Decreases Recognition Memory in Adult Male Rats. Current Psychopharmacology 2(3): 247-253.

De Medeiros GF, Pereira E, Granzotto N, Ramos A. (2013). Low-anxiety rat phenotypes can be further reduced through genetic intervention. PLoS One. 2013 Dec 30;8(12):e83666.

Santos JR, Cunha JA, Dierschnabel AL, Campêlo CL, Leão AH, Silva AF, Engelberth RC, Izídio GS, Cavalcante JS, Abílio VC, Ribeiro AM, Silva RH. (2013). Cognitive, motor and tyrosine hydroxylase temporal impairment in a model of parkinsonism induced by reserpine. Behav Brain Res 15;253:68-77.

De Macêdo Medeiros A, Izídio GS, Sousa DS, Macedo PT, Silva AF, Shiramizu VK, Cabral A, Ribeiro AM, Silva RH.  (2014). Estrogen levels modify scopolamine-induced amnesia in gonadally intact rats. Prog Neuropsychopharmacol Biol Psychiatry 4;53:99-108.

Leão AH, Cabral A, Izídio GS, Ribeiro AM, Silva RH. (2015). Diazepam effects on aversive memory retrieval and extinction: Role of anxiety levels. Pharmacology, Biochemistry and Behavior 141:42-9.

Anselmi M, Correa FJ, Santos JR, Silva AF, Cunha JA, Leão AH, Campelo CL, Ribeiro AM, Silva RH, Izídio GS. (2016). Genetic evidence for chromosome 4 loci influencing learning and memory. Neurobiology of Learning and Memory (Print) 131:182-91.

Silva AF, Sousa DS, Medeiros AM, Macêdo PT, Leão AH, Ribeiro AM, Izídio GS, Silva RH. (2016). Sex and Estrous Cycle Influence Diazepam Effects on Anxiety and Memory: Possible Role of Progesterone. Progress in Neuro-Psychopharmacology & Biological Psychiatry 3;70:68-76.

PERTILE, R. A. N. ; CORVINO, M. E. ; MARCHETTE, R. C. N. ; PAVESI, E. ; CAVALLI, J. ; RAMOS, A. ; IZÍDIO, G. S. . The quinpirole hypolocomotive effects are strain and route of administration dependent in SHR and SLA16 isogenic rats. BEHAVIOR GENETICS, v. 1, p. 1-12, 2017.

CAMPÊLO, CLARISSA L.C ; CAGNI, FERNANDA C. ; DE SIQUEIRA FIGUEREDO, DIEGO ; OLIVEIRA JR., LUIZ G. ; SILVA-NETO, ANTÔNIO B. ; MACÊDO, PRISCILA T. ; Santos, José R. ; Izídio, Geison S. ; Ribeiro, Alessandra M. ; DE ANDRADE, TIAGO G. ; DE OLIVEIRA GODEIRO, CLÉCIO ; Silva, Regina H. . Variants in SNCA Gene Are Associated with Parkinson?s Disease Risk and Cognitive Symptoms in a Brazilian Sample. Frontiers in Aging Neuroscience, v. 9, p. 1-13, 2017.

MAZUR, F. G. ; OLIVEIRA, L. F. G. ; CUNHA, M. P. ; RODRIGUES, A. L. ; PERTILE, R. A. N. ; VENDRUSCOLO, L. F. ; IZÍDIO, G. S. . EFFECTS OF PHYSICAL EXERCISE AND SOCIAL ISOLATION ON ANXIETY-RELATED BEHAVIORS IN TWO INBRED RAT STRAINS. BEHAVIOURAL PROCESSES, p. 70-78, 2017.

LEÃO, ANDERSON HENRIQUE ; MEURER, Y. S. R. ; SILVA, ANATILDES FEITOSA ; MEDEIROS, ANDRÉ MACÊDO ; CAMPELO, C.L.C. ; Abílio, Vanessa C. ; ENGELBERTH, R. C. G. J. ; CAVALCANTE, J. S. ; IZÍDIO, G. S. ; Ribeiro, Alessandra M. ; SILVA, REGINA HELENA . Spontaneously Hypertensive Rats (SHR) Are Resistant to a Reserpine-Induced Progressive Model of Parkinson’s Disease: Differences in Motor Behavior, Tyrosine Hydroxylase and α-Synuclein Expression. Frontiers in Aging Neuroscience, v. 9, p. 78, 2017.

ACUNA, L. R. ; MARCHETTE, R. C. N. ; GRANZOTTO, N. ; DIAS, P. G. ; CORVINO, M. E. ; MAZUR, F. G. ; CORREA, F. J. ; IZÍDIO, G. S. . EFFECTS OF REPEATED TREATMENT WITH MIDAZOLAM IN SHR AND SLA16 RAT STRAINS IN THE TRIPLE TEST. BEHAVIOR GENETICS, v. 48, p. 440-450, 2018.

VELÁZQUEZ, ANA MAGDALENA ; ROVERSI, KATIANE ; DILLENBURG-PILLA, PATRICIA ; RODRIGUES, RODRIGO FERRACINE ; ZÁRATE-BLADÉS, CARLOS R. ; PREDIGER, RUI DANIEL S. ; IZÍDIO, GEISON SOUZA . The influence of chromosome 4 on metabolism and spatial memory in SHR and SLA16 rat strains. BEHAVIOURAL BRAIN RESEARCH, p. 111966, 2019.

França, Angela Patricia ; SCHAMNE, M. G. ; SOUZA, B. S. ; SCHEFFER, D. L. ; BERNARDELLI, A. ; CORREA, T. ; IZÍDIO, G. S. ; LATINI, A. ; SANTOS, J. E. S. ; CANAS, P. ; CUNHA, R. A. . Caffeine consumption plus physical exercise improves behavioral impairments and stimulates neuroplasticity in spontaneously hypertensive rats (SHR) ? an animal model of Attention Deficit Hyperactivity Disorder. Molecular Neurobiology, v. 57, p. 3902-3919, 2020.

PEREIRA, A. G. ; POLI, A. ; MATHEUS, F. C. ; SILVA, L. B. ; FADANNI, G. ; IZÍDIO, G. S. ; LATINI, A. ; PREDIGER, RUI DANIEL S. . Temporal development of neurochemical and cognitive impairments following reserpine administration in rats. BEHAVIOURAL BRAIN RESEARCH, v. 383, p. 112517, 2020.

FRANCA, A. P. ; SCHAMNE, M. G. ; SOUZA, B. S. ; SCHEFFER, D. L. ; BERNARDELLI, A. ; CORREA, T. ; IZÍDIO, G. S. ; LATINI, A. ; SANTOS, J. E. S. ; CANAS, P. ; CUNHA, R. A. ; PREDIGER, R. D. . Agmatine improves olfactory and cognitive deficits in Spontaneously Hypertensive Rats (SHR): An animal model of Attention Deficit Hyperactivity Disorder (ADHD).. BEHAVIORAL NEUROSCIENCE, v. 78, p. 2280-2285, 2021.

Leão, Anderson H.F.F. ; MEURER, YWLLIANE S.R. ; FREITAS, THALMA A. ; Medeiros, André M. ; Abílio, Vanessa C. ; Izídio, Geison S. ; CONCEIÇÃO, ISALTINO M. ; Ribeiro, Alessandra M. ; Silva, Regina H. . Changes in the mesocorticolimbic pathway after low dose reserpine-treatment in Wistar and Spontaneously Hypertensive Rats (SHR): Implications for cognitive deficits in a progressive animal model for Parkinson?s disease. BEHAVIOURAL BRAIN RESEARCH, v. 410, p. 113349, 2021.

ANJOS, PÂMELA ANDRESSA RAMBORGER DOS ; MARCHETTE, RENATA CRISTINA NUNES ; KREMER, RAFAEL ; Granzotto, Natalli ; ALVES, THALITA MELLO ; FADANNI, GUILHERME PASETTO ; MAZUR, FERNANDO GABRIEL ; ANTON, ELAINE LEOCÁDIA ; DA SILVA SANTOS, JOSÉ EDUARDO ; LINDER, ÁUREA ELIZABETH ; IZÍDIO, GEISON SOUZA . The influence of chromosome 4 on high ethanol consumption and blood pressure. ALCOHOL, v. 102, p. 1-10, 2022.